| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Alkaline Phosphatase, Bone Specific [29498]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
ALKBNE
CPT Codes
84075
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Non-serum samples • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-2 days
Reference Range
| Adult Male | |
| 18-29 years | 8.4-29.3 mcg/L |
| 30-39 years | 7.7-21.3 mcg/L |
| 40-49 years | 7.0-18.3 mcg/L |
| 50-68 years | 7.6-14.9 mcg/L |
| >68 years | Not established |
| Adult Female | |
| 18-29 years | 4.7-17.8 mcg/L |
| 30-39 years | 5.3-19.5 mcg/L |
| 40-49 years | 5.0-18.8 mcg/L |
| 50-76 years | 5.6-29.0 mcg/L |
| >76 years | Not established |
| Premenopausal | |
| 35-45 years | 5.0-18.2 mcg/L |
| Pediatric | Male (mcg/L) | Female (mcg/L) |
| 2-24 months** | 25.4-124.0 | 25.4-124.0 |
| 25 months-5 years | Not established | Not established |
| 6-9 years | 41.0-134.6 | 41.0-134.6 |
| 10-13 years | 43.8-177.4 | 24.2-154.2 |
| 14-17 years | 13.7-128.0 | 10.5-75.2 |
Clinical Significance
The bone-specific alkaline phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
Last Updated: November 24, 2021
