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Human Anti-mouse Antibody (HAMA) [1468]
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Test Code
HAMA
Alias/See Also
1468
CPT Codes
83520
Preferred Specimen
1 mL frozen serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature = 7 days
Refrigerated = 14 days
Frozen = 30 days
Refrigerated = 14 days
Frozen = 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross lipemia • Serum separator tube (SST®)
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
Set up: Thurs a.m.; Report available: 7-14 days
Reference Range
≤74 ng/mL
Clinical Significance
The presence of Human Anti-mouse Antibody (HAMA) has been associated with patients receiving injections of Murine Monoclonal Antibody (MAB) for diagnostics and/or therapeutic purposes. HAMA produced in response to monoclonal antibody therapy may interfere with therapeutic efficacy. Therefore, it is recommended that baseline HAMA levels are determined prior to the initiation of therapy with murine-derived proteins.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Last Updated: November 30, 2021
