Rickettsia Antibody Panel with Reflex to Titers [37507]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
RCKAB


Alias/See Also
37507


CPT Codes
86757 (x4)

Includes
Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers
Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

If Rickettsia (RMSF) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).
If Rickettsia (Typhus Fever) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).


Preferred Specimen
1 mL serum


Minimum Volume
0.2 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia


Methodology
Immunofluorescent Assay (IFA)

Setup Schedule
Set up: Tues-Sat a.m.; Report available: Next day


Limitations
Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.


Reference Range
Screen Titer
RMSF IgG Not detected <1:64
RMSF IgM Not detected <1:64
R. typhi IgG Not detected <1:64
R. typhi IgM Not detected <1:64


Clinical Significance
Antigen-specific IgG and IgM titers allow rapid diagnosis of infection by organisms within either of the two major groups of Rickettsia. The spotted fever group includes R. rickettsia (Rocky Mountain Spotted Fever) and R. akari (Rickettsial pox). The typhus group includes R. typhi (endemic/murine typhus) and R. prowazeki (epidemic typhus).


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



Last Updated: December 6, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.