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Intrinsic Factor Blocking Antibody [568]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
INTFAB
Alias/See Also
568
CPT Codes
86340
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Instructions
Samples should not be collected from a patient who has received vitamin B12 injection therapy within the past week.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-2 days
Reference Range
Negative
Clinical Significance
Intrinsic Factor, produced by cells lining the stomach, binds Vitamin B12 (cyanocobalamin) to facilitate absorption of the vitamin. Blocking antibody impedes the action of Intrinsic Factor as observed in approximately half of the patients who develop pernicious anemia.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
Last Updated: November 30, 2021
