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Histamine, 24-Hour Urine [4946X]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
HISTMU
Alias/See Also
4946
CPT Codes
83088
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
4 mL urine from a 24-hour urine containing 10 mL 6N HCL collected in a leak-proof container
Patient Preparation
Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.
Minimum Volume
2 mL
Other Acceptable Specimens
Urine with no preservative
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Methodology
Immunoassay (IA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
Set up: Tues, Fri; Report available: 1-5 days
Reference Range
0.006-0.131 mg/24 h
Clinical Significance
Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Last Updated: November 30, 2021
