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Calprotectin, Stool [16796]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
CALPRO
Alias/See Also
16796
CPT Codes
83993
Preferred Specimen
Preferred:
3 grams (0.3 gram minimum) solid stool collected in a clean leak-proof plastic screw-cap container without preservative
Acceptable:
Liquid or semi-liquid stool
3 grams (0.3 gram minimum) solid stool collected in a clean leak-proof plastic screw-cap container without preservative
Acceptable:
Liquid or semi-liquid stool
Minimum Volume
0.3 grams
Other Acceptable Specimens
Liquid or semi-liquid stool collected in a Quest standard stool container without preservative, or a clean, leak-proof plastic screw-cap container without preservative
Instructions
Collect stool specimen in a clean leak-proof plastic screw-cap container without preservative.
Transport Temperature
Frozen
Specimen Stability
Room temperature = Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at Room Temperature.
Refrigerated = 7 days
Frozen = 28 days
Refrigerated = 7 days
Frozen = 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Stool specimen collected in a container with fixative or preservative • Stool specimen collected during surgical procedure • Other specimen rather than raw stool sample
Methodology
Chemiluminescence
Setup Schedule
Mon-Sat
Report Available
4-5 days
Limitations
NSAIDs may cause elevated results.
Reference Range
<50 mcg/g | Normal |
50-120 mcg/g | Borderline |
>120 mcg/g | Elevated |
Clinical Significance
Calprotectin is a non-specific marker of bowel inflammation. Subsequent to white blood cell migration into the intestine, this neutrophil protein may be detected in the stool. Thus, fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease; Crohn's disease and ulcerative colitis and other disorders characterized by bowel inflammation. It can also be used as an aid in the differentiation of IBD from irritable bowel syndrome.
Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675
Last Updated: October 17, 2022