Calprotectin, Stool [16796]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
CALPRO


Alias/See Also
16796


CPT Codes
83993

Preferred Specimen
Preferred:
3 grams (0.3 gram minimum) solid stool collected in a clean leak-proof plastic screw-cap container without preservative

Acceptable:
Liquid or semi-liquid stool


Minimum Volume
0.3 grams


Other Acceptable Specimens
Liquid or semi-liquid stool collected in a Quest standard stool container without preservative, or a clean, leak-proof plastic screw-cap container without preservative


Instructions
Collect stool specimen in a clean leak-proof plastic screw-cap container without preservative.


Transport Temperature
Frozen


Specimen Stability
Room temperature = Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at Room Temperature.
Refrigerated = 7 days
Frozen = 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Stool specimen collected in a container with fixative or preservative


Methodology
Chemiluminescence

Setup Schedule
Mon-Sat


Report Available
4-5  days


Limitations
NSAIDs may cause elevated results.


Reference Range
<50 mcg/g Normal
50-120 mcg/g Borderline
>120 mcg/g Elevated


Clinical Significance
Calprotectin is a non-specific marker of bowel inflammation. Subsequent to white blood cell migration into the intestine, this neutrophil protein may be detected in the stool. Thus, fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease; Crohn's disease and ulcerative colitis and other disorders characterized by bowel inflammation. It can also be used as an aid in the differentiation of IBD from irritable bowel syndrome.


Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675


Last Updated: October 17, 2022


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.