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RPR (Monitor) with Reflex to Titer
Test CodeRPRTT,RPRQ1
Quest Code
799
CPT Codes
86592
Includes
If RPR Screen is reactive, then RPR titer will be performed at an additional charge (CPT code(s): 86593).
Preferred Specimen
1 mL serum
Minimum Volume
0.6 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Flocculation
Setup Schedule
Mon, wed-sat
Report Available
2-5 days
Limitations
False-positive results have been associated in patients with infections, pregnancy, autoimmune disease, old age, Gaucher disease, and malignancy.
Reference Range
Non-Reactive
Clinical Significance
This is a nontreponemal (lipoidal antigen) serologic test used to monitor patients diagnosed with syphilis. RPR reactive samples will be reflexed to titer. Titer results may correlate with disease activity and typically decrease in response to treatment.
Serologic evaluation is recommended at 6 to 12 months for primary and secondary syphilis. Follow-up testing should be performed using the same nontreponemal (lipoidal antigen) test and be performed by the same laboratory so that results are comparable over time.
True positive results with nontreponemal (lipoidal antigen) tests may occur due to wide range of biological conditions (e.g., autoimmune disease, cancer, infectious diseases, old age, and pregnancy).
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
