AFP for California Alpha Fetoprotein screening program
 

Test Code
AFP Prenatal


Alias/See Also
Alpha Fetoprotein, AFP
First Trimester AFP
Second Trimester AFP
Prenatal AFP


Physician Attestation of Informed Consent
The prenatal AFP test is performed only on pregnant women who are participating in the California Alpha-Fetoprotein Screening Program.  It is performed on either first or second trimester patients.  To have this specimen drawn, the patient must have completed AFPI form from their physician containing the required patient identification and information.


Preferred Specimen
GOLD (SST)
3.5 ml Gold


Patient Preparation
AFPI Form completed by physician. If the patient does not have this form, the test cannot be performed.
  • Blue  Form:  First Trimester Screening for patients 10 weeks 0 days to 13 weeks 6 days.
  • Green Form:  SecondTrimester Screening for patients 15 Weeks 0 days to 20 Weeks 0 days.


Instructions

  1. Obtain completed AFPI form and copy of patient's insurance card.  Register patient in EPIC for VENOP charge.

  2. Collect specimen in required 3.5ml SST vacutainer following standard venipuncture procedure.

  3. Write patient’s Name and collection date on AFPI label underneath AFP number located on top sheet of form. Place the AFPI label on the specimen. (Note:  Label is blue for 1st trimester and white for second trimester)

  4. Fill out Part B of AFPI form with collection date, facility location, facility phone number and collector’s initials.

  5. Invert specimen gently 5 times.

  6. Label specimen with AFP label from step 3.

  7. Allow specimen to stand 1/2 hr to 1 hr before centrifuging to aid clot formation. 

  8. Centrifuge specimen. 

  9. Place specimen in biohazard bag.  Place white Original form in outer pouch.

  10. Deliver specimen and form to AFP box located in CRMC Phlebotomy area.

  11. Place yellow and/or pink copy of form with face sheet to be filed in the outpatient requisition file.




Clinical Significance
For pregnant women, to assess the risk of having a baby with certain chromosomal disorders, such as Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18), or open neural tube defects, such as spina bifida. 


Performing Laboratory
Collection:  CRMC Outpatient Laboratory

Testing performed:  Newborn and Prenatal Laboroatory (NAPS)



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.