Estimated Glomerular Filtration Rate

Message

INCLUDED IN MET10, Cm10, CMP, RENAL PANELS

Test Code

EGFR, EGFR1, EGFR2

Alias/See Also

GFR, EGFR, Glomerular Filtraion Rate, EGFR1, EGFR2

Reference Range

CMC Laboratories are pleased to announce the transition to the National Kidney Foundation and the American Society of Nephrology recommendation from 2021 to use race-free calculations/equations to estimate GFR.

Available Facilities: CRMC, CCMC, FHSH, and CCI

Test Order Information: The calculation is included in standard chemistry panels that include creatinine. Examples include:

CMP: Comprehensive Metabolic Panel
MET10: Basic Metabolic Panel
CM10: Basic Metabolic Panel with Ionized Ca
Renal Function Panel
Creatinine

Effective Date: April 23, 2026. Change will go into effect approximately Noon. All labs resulted after this time will have the new eGFR calculated result.

Calculation Information/Highlights:

Current eGFR Calculation/Equation: MDR
(MDR = Modification of diet in renal disease)
Estimates GFR Using serum creatinine, age, sex, and RACE

Reference range and Comment:
GFR is estimated using the MDRD equation recommended by the National Kidney Disease Education Program.

Comment:
Estimated GFR Interpretive Information: (EGFR/mL/min/1.73m2)
>90: Normal - if no other evidence of kidney disease present.
Chronic Kidney Disease Stage 1 - if there is evidence
of kidney disease present such as proteinuria, hematuria,
genetic kidney disease, or structural abnormality.
60-89: Chronic Kidney Disease Stage 2 (Mild)
30-59: Chronic Kidney Disease Stage 3 (Moderate)
15-29: Chronic Kidney Disease Stage 4 (Severe)
<15: Chronic Kidney Disease Stage 5 (End Stage, Kidney Failure)
* GFR must be <60 mL/min/1.73m2 for at least 3 months to meet the definition of Chronic Kidney Disease.

New eGFR Calculation/Equation: CKD-EPI
(CKD-EPI = Chronic kidney disease-epidemiology)
Estimates GFR from serum creatinine, age, and sex

Reference range and Comment:
GFR is estimated using the calculation based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation refit without adjustment for race.

Comment:
Estimated GFR Interpretive Information: (EGFR/mL/min/1.73m2)
>90: Normal - if no other evidence of kidney disease present.
Chronic Kidney Disease Stage 1 - if there is evidence
of kidney disease present such as proteinuria, hematuria,
genetic kidney disease, or structural abnormality.
60-89: Chronic Kidney Disease Stage 2 (Mild)
30-59: Chronic Kidney Disease Stage 3 (Moderate)
15-29: Chronic Kidney Disease Stage 4 (Severe)
<15: Chronic Kidney Disease Stage 5 (End Stage, Kidney Failure)
* GFR must be <60 mL/min/1.73m2 for at least 3 months to meet the definition of Chronic Kidney Disease.

Performing Laboratory
CRMC Laboratory
CCMC Laboratory
FHSH Laboratory

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.