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Cancer Antigen 15-3
Test CodeCA15F
Alias/See Also
15-3, Cancer Antigen, CA15-3
CPT Codes
86300
Preferred Specimen
Light Green (PST)
Other Acceptable Specimens
Serum (Red) or Gold (SST) or Orange (OJ) or Tiger Top Serum
Instructions
Allow serum samples to clot completely before centrifugation.
Keep tubes stoppered at all times.
Within two hours after centrifugation, transfer at least 500 microliters of cell-free sample to a storage tube and tightly stopper.
Keep tubes stoppered at all times.
Within two hours after centrifugation, transfer at least 500 microliters of cell-free sample to a storage tube and tightly stopper.
Specimen Stability
Store samples tightly stoppered at room temperature (15-30°C) for no longer than eight hours.
If the assay will not be completed within eight hours, refrigerate the samples at 2-8°C.
If the assay will not be completed within 48 hours, or for shipment of samples, freeze at -20°C or colder. Thaw samples only once.
If the assay will not be completed within eight hours, refrigerate the samples at 2-8°C.
If the assay will not be completed within 48 hours, or for shipment of samples, freeze at -20°C or colder. Thaw samples only once.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Lipemia
Methodology
Beckman DXI
Setup Schedule
24x7
Reference Range
0-31.3 U/mL
Clinical Significance
CA 15-3 antigen levels are elevated in many patients with epithelial breast carcinoma. Elevated levels of CA 15-3 antigen may also be present in those patients with lung, ovarian, pancreatic, and colorectal cancers, as well as non-malignant conditions including benign breast and liver disease, cirrhosis, and hepatitis.
CA 15-3 antigen, has become a widely recognized breast cancer marker and has shown to be more sensitive than CEA in detecting recurrence of breast cancer. Increasing CA 15-3 antigen levels may be representative of disease progression, whereas, decreasing antigen levels may be associated with disease regression.
CA 15-3 antigen, has become a widely recognized breast cancer marker and has shown to be more sensitive than CEA in detecting recurrence of breast cancer. Increasing CA 15-3 antigen levels may be representative of disease progression, whereas, decreasing antigen levels may be associated with disease regression.
Performing Laboratory
CRMC Laboratory
