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Tobramycin Level
MessageFor patients on a regimen of divided daily tobramycin doses, collect a peak sample 30 - 60 minutes after intravenous infusion or 60 - 90 minutes after intramuscular injection.
Collect trough samples just before the next scheduled dose.
When adjusting dosage, measure peak and trough levels over the same dosing interval to obtain accurate estimates of half-life and clearance.
Collect trough samples just before the next scheduled dose.
When adjusting dosage, measure peak and trough levels over the same dosing interval to obtain accurate estimates of half-life and clearance.
Test Code
TOBRP, TOBRR, TOBRT
Alias/See Also
Tobramycin Peak, TOBRP, Tobraycin Trough, TOBRT, Tobramycin Random, TOBRR
CPT Codes
80200
Preferred Specimen
Serum: RED (RED)
Other Acceptable Specimens
Plasma: EDTA (LAV), Heparin (GRN)
Specimen Stability
Sample Stability:
- Refrigerator Temperature: Store the serum or plasma refrigerated at 2-8°C. for up to one month.
- Freezer Temperature: Store serum or plasma frozen (≤-20°C) for up to 1 month.
Methodology
Beckman AU
Setup Schedule
24x7
Limitations
AMR: 0.6-60.0 ug/mL
Reference Range
Tobramycin Trough: 0.0-1.9 ug/mL Critical: > 3.0 ug/mL
Tobramycin Peak: 5.0-10.0 ug/mL Critical: >14.0 ug/mL
Tobramycin Random: 0.0-10.0 ug/mL Critical: >14.0 ug/mL
Tobramycin Peak: 5.0-10.0 ug/mL Critical: >14.0 ug/mL
Tobramycin Random: 0.0-10.0 ug/mL Critical: >14.0 ug/mL
Clinical Significance
Tobramycin is an aminoglycoside antibiotic used to treat infections caused by many different bacteria.
Performing Laboratory
CRMC Laboratory
