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Varicella Zoster AB IgG
Test CodeVZVIG
Alias/See Also
Chicken Pox, Varicella, VZV
CPT Codes
86787
Preferred Specimen
Serum Gold (SST)
Other Acceptable Specimens
Red
Only serum is acceptable
Only serum is acceptable
Instructions
- Collect 1 gold topped, serum separator tube. No anticoagulants or preservatives should be added.
- Allow tubes to clot adequately before centrifugation.
- Avoid using hemolyzed, lipemic, or bacterially contaminated sera.
Specimen Stability
- Eight (8) hours at room temperature.
- Forty eight (48) hours at refrigerator temperature 2° and 8°C degrees.
- If delay in testing is beyond 48 hours, store test sera at -20°C or lower. Avoid multiple freeze/thaw cycles that may cause loss of antibody activity and give erroneous results.
Methodology
ELISA
Setup Schedule
M-F, 8 am to 5 pm
Reference Range
Index Value for Varicella Ab, IgG:
The results of this test system are qualitative. The magnitude of the ratio for positive specimens may not correlate with antibody titer. If testing a particular sample occurs early during primary infection, no detectable IgG may be evident. If Varicella infection is suspected, a second sample should be taken at least fourteen days later.
- Negative: 0.89 IV or less: Indicates no detectable IgG antibodies to Varicella virus. No current or previous infection with Varicella. Patient is presumed to be non-immune and are therefore susceptible to a primary infection.
- Equivocal: 0.90 - 1.09 IV: Specimens with OD ratio values in the equivocal range should be re-tested in a few weeks or by an alternate serologic method.
- Positive: Greater 1.10 IV: Indicates a past or current infection with Mumps and that the patient should be considered immune to Varicella primary infection.
The results of this test system are qualitative. The magnitude of the ratio for positive specimens may not correlate with antibody titer. If testing a particular sample occurs early during primary infection, no detectable IgG may be evident. If Varicella infection is suspected, a second sample should be taken at least fourteen days later.
Clinical Significance
Aid in the determination of immune status and/or aid in diagnosis of Varicella infections.
Performing Laboratory
CRMC Microbiology/Immunology Laboratory
