P2Y12 (Plavix)TEST

1. Sample must be collected to a Greiner 2.0 ml partial filled blue top tube containing 3.2% sodium citrate. The sample must be filed to the small black line.
2. Obtain the sample after a discard tube of at least 2 ml. Do not draw a sample for P2Y12 assay after a tube that contains EDTA (purple top).
3. For collection a 21 gauge or larger needle must be used to avoid platelet activation.
4. The collected sample must be inverted gently for at least 5 times.
5. Samples must be incubated at room temperature for 10 minutes prior to testing and can be used up to 4 hours after collection. 
6. Samples must be delivered to the department in an upright position. NOTE: Do Not Send through the tube system and do not centrifuge.
7. Do not refrigerate or freeze specimen.

P2YR Units:  194-418 PRU

The Verify Now P2Y12 test reports the PRU result.  P2Y12 Reaction Units (PRU) report the amount of P2Y12 receptor mediated aggregation specific to the platelet and is calculated as a function of the rate and extent of platelet aggregation in the ADP channel.

Patients not receiving the expected effect of their antiplatelet medication (PRU greater than 207) are at an increased risk of recurrent cardiovascular events such as stent thrombosis, myocardial infarction and death.
Patients receiving too much effect of their anitplatelet medications (PRU <95) are at a signicicantly increased risk for major bleeding.