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Lupas Antocoagulant Screen
Test CodeLUPAN
Alias/See Also
Lac Screen.
CPT Codes
0
Includes
- LAC Screen,
- PT and Mixing PT
- PTT, and Mixing PTT, Incubation PTT
- Mixing Studies
- STACLOT
- Interpretation/Consultation
Preferred Specimen
BLUE (BLU) 2 tubes
Transport Container
If testing is to be delayed more than four hours after collection, immediately separate plasma into a clean, polystyrene tube, cap, and store below –20°C up to 2 weeks and -70°C upt 6 months.
Specimen Stability
Store below –20°C up to 2 weeks and -70°C upt 6 months.
Setup Schedule
Setup Testing: Monday and Thursday
(Subject to variation on Holidays and staffing fluctuations)
(Subject to variation on Holidays and staffing fluctuations)
Report Available
Reference Range
Clinical Significance
Lupus anticoagulants are immunoglobulins that generally interfere with the Activated Partial Thromboplastin time (APTT) Assay. The common association of LA with thrombocytopenia, recurrent spontaneous abortions, and idiopathic thromboembolic diseases underlines the importance of diagnostic tests capable of distinguishing these LA antibodies from anti-factor antibodies, factor deficiencies, and heparin effect, since all four conditions may cause a prolongation of the APTT test.
The STAClot LA procedure is performed whenever the preliminary workup (APTT, PT, and LAC screen) is abnormal and mixing studies do not correct to normal.
Performing Laboratory
CRMC Laboratory
