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Aspirin Resistance Assay

Test Code
ASPR


Alias/See Also
Verify Now Aspirin, Aspirin, Platelet Function


CPT Codes
85576

Preferred Specimen
2 Greiner Blue tops (BSP)  [Greiner 2.0 mL partial fill special BLU 3.2% Sodium Citrate tube].


Instructions
  1. Sample must be collected to a Greiner 2.0 ml partial filled blue top tube containing 3.2% sodium citrate. The sample must be filed to the small black line.
  2. Obtain the sample after a discard tube of at least 2 ml. Do not draw a sample for Aspirin assay after a tube that contains EDTA (purple top).
  3. For collection a 21 gauge or larger needle must be used to avoid platelet activation.
  4. The collected sample must be inverted gently for at least 5 times.
  5. Samples should be collected between 2 to 30 hours after ingestion of aspirin.
  6. Sample must be incubated at room temperature for 30 minutes prior to testing and can be used up to 4 hours after collection. Do Not Refrigeration or freeze specimen.
  7. Samples must be delivered to the department in an upright position. NOTE: Do Not Send through the tube system and do not centrifuge


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens sent through pneumatic tube system.
Specimens > 4 hours old


Methodology
Verify Now platform

Setup Schedule
24x7


Reference Range
Therapeutic range: less than 550 ARU
Non-therapeutic range: greater than 549 ARU
The results are reported in Aspirin Reaction Units (ARU), which indicate the amount of thrombxane A2-mediated activation of glycoprotein IIb/IIa receptors involved in platelet aggregation. The lower value, the more inhibition is present, consistent with a reponse to aspirin.


Clinical Significance
VerifyNow Aspirin is a rapid diagnostic test designed specifically to measure aspirin response.


Performing Laboratory
CRMC Laboratory
CCMC Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.