Transferrin

Test Code
TRANF


CPT Codes
84466

Preferred Specimen
SST (GOLD) Serum


Other Acceptable Specimens
Serum (Red) or Gold (SST) or Orange (OJ) or Tiger Top Serum
EDTA Lav


Instructions
An 8 to 12 hour fast is recommended, but not required, in order to minimize any possible lipemia.


Specimen Stability
Serum samples are stable for 40 days at <= -20oC. and can be repeatedly frozen and thawed without loss of immunological activity.


Setup Schedule
24x7


Reference Range
Female:  250-380 mg/dL
Male:      215-365 mg/dL


Clinical Significance

Iron in plasma is bound to the transport protein transferrin. Transferrin is responsible for 50% to 70% of the iron binding capacity of serum. Transferrin has two iron-binding sites and is largely, but not exclusively, synthesized by the liver.




Transferrin levels rise with iron deficiency and fall in cases of iron overload. Increase in transferrin is seen in iron deficiency anemia. It may also be increased late in pregnancy and in women on oral contraceptives. It is decreased in conditions associated with increased protein loss, such as nephrotic syndrome, chronic renal failure, severe burns, and protein-deficiency states and in severe liver disease. Transferrin is a negative acute-phase protein and will be decreased during any inflammatory state or severe illness.




Performing Laboratory
CRMC Laboratory
CCMC Laboratory
CCI Laboratory



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.