LDH, Lactate Dehydrogenase

Test Code

LDH

Alias/See Also

LDH, LD, Lactate dehydrogenase

CPT Codes
83615

Preferred Specimen

Light GREEN (PST)

Other Acceptable Specimens

Serum (Red) or Gold (SST) or Orange (OJ) or Tiger Top Serum

Instructions

No hemolysis. Centrifuge immediately.

Specimen Stability

The stability of LD in serum/body fluids at different storage temperatures has been studied by various investigators. Although the results are inconsistent, it has been established that heart isoenzymes are more stable than liver isoenzymes. In any event, it is essential that a standard collection and storage procedure be adopted to ensure consistent results. It is better not to refrigerate or freeze specimens, but to hold it at room temperature (15 - 25°C) with analysis done as soon as possible.

Methodology
Beckman AU

Setup Schedule

_24x7

Report Available

<1 day

Reference Range

LDH: 100-230 U/L

Clinical Significance

Clinical Significance in Serum/Plasma: LDH is a non-specific test that may be used in the evaluation of a number of diseases and conditions. LDH is found in all cells of the body (as well as bacteria), with extremely high levels found in specific tissues such as the heart, liver, kidneys, skeletal muscle, and erythrocytes and is released from cells when they are damaged or destroyed. Therefore, increased levels seen in serum can be directly related to the damage of one of these tissues. Tissue levels of LDH are 500-fold higher than whole blood levels. Such measurements are used in the diagnosis and treatment of myocardial infarction, pulmonary emboli, liver disease, pernicious and megaloblastic anemias, malignancies, and muscular dystrophy. The results also may be used to monitor cancer chemotherapy.

Performing Laboratory
CRMC Laboratory
CCMC Laboratory
CCI Laboratory
FHSH Laboratory

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.