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GGT:Gamma-Glutamyltransferase
Test CodeGGT
Alias/See Also
GGT, Gamma GT
CPT Codes
82977
Preferred Specimen
Plasma Light Green (PST)
Other Acceptable Specimens
Serum (Red) or Gold (SST) or Orange (OJ) or Tiger Top Serum
Specimen Stability
The GGT determination should be performed as soon after specimen collection as possible. GGT in serum is stable for 1 month refrigerated at 2-8ºC and 1 year frozen at ≤-20ºC.
Setup Schedule
24x7
Reference Range
Female: 1-24 IU/L
Male: 2-30 IU/L
Values may vary with age, sex, diet , and geographical location.
Male: 2-30 IU/L
Values may vary with age, sex, diet , and geographical location.
Clinical Significance
The gamma-glutamyl transferase (GGT) test may be used to determine the cause of elevated alkaline phosphatase (ALP). Both ALP and GGT are elevated in disease of the bile ducts and in some liver diseases, but only ALP will be elevated in bone disease. Therefore, if the GGT level is normal in a person with a high ALP, the cause of the elevated ALP is most likely bone disease.
The GGT test is sometimes used to help detect liver disease and bile duct obstructions. It is usually ordered in conjunction with or as follow up to other liver tests such as ALT, AST, ALP, and bilirubin. In general, an increased GGT level indicates that a person's liver is being damaged but does not specifically point to a condition that may be causing the injury.
GGT can be used to screen for chronic alcohol abuse (it will be elevated in about 75% of chronic drinkers) and to monitor for alcohol use and/or abuse in people who are receiving treatment for alcoholism or alcoholic hepatitis
Performing Laboratory
CRMC Laboratory
