| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Carboxyhemoglobin Panel
Test CodeCOHB, COHB1
Alias/See Also
Carbon Monoxide
CPT Codes
82375
Includes
Total HGB (HGBCT) , OxyHgb (O2HB), CarboxyHGB (HBCO), MetHgb NETHB), O2 Content (O2CT), Reduced HGB (HGBR)
Preferred Specimen
Syringe, Li Heparinized (SYR)
DK Grn (NO GEL)
DK Grn (NO GEL)
Minimum Volume
100 uL
Other Acceptable Specimens
Na Heparin WB, Dark Green (GRN)
Instructions
Arterial must be delivered on ice. Venous may be room Temp. Do not centrifuge
Methodology
Blood Gas Analyzers
Reference Range
| Test | Age and Gender | Reference Range | Critical Low | Critical High | |
| Arterial | Venous | ||||
| HGBCT Total Hgb (g/dL) | 0-14 days | 12.5-24.5 | <7.0 | >30.0 | |
| 14-60 days | 10.7-17.3 | <7.0 | >30.0 | ||
| 60 days to 24 Months | 9.9-14.5 | <7.0 | >30.0 | ||
| 2-6 Years | 10.3-14.9 | <5.0 | >30.0 | ||
| 6-11 Years | 10.6-15.2 | <5.0 | >30.0 | ||
| 11-15 Years | 11.1-15.7 | <5.0 | >30.0 | ||
| Female > 15 Years | 12.0-16.0 | <5.0 | >30.0 | ||
| Male >15 Years | 14.0-18.0 | <5.0 | >30.0 | ||
| O2HB: Oxyhemoglobin (%) | ALL | 94-97% | 40-70 % | ||
| HBCO: Carboxyhemoglobin (%) | ALL | 0.0-1.5 % | 0.0-1.5 % | ||
| METHB: Methemoglobin | All (Non-Smoker) | 0.4-1.5% | 0.4-1.5% | ||
| ALL (Smoker) | 1.5-5.0% | 1.5-5.0% | |||
| O2CT: Oxygen Content (%VOL) | Female | 15-21 Vol% | 6.7-15.6 Vol% | ||
| Male | 18-26 Vol% | 7.5-17.5 Vol% | |||
| HGBR: Reduced Hemoglobin | |||||
Clinical Significance
- Carboxyhemoglobin (COHb): Measurement of carboxyhemoglobin indicates if and to what extent carbon monoxide has been inhaled by the patient. Because the affinity of hemoglobin for carbon monoxide is about 210 times greater than its affinity for oxygen, high levels of CO can lead to tissue anoxia and death unless diagnosed early.
- Methemoglobin (MetHb): Elevations in methemoglobin concentration can be due to congenital methemoglobinemia or from the ingestion of nitrates, chlorates, or any other drug or chemical that can cause methemoglobin formation (oxidation of Iron +2 to +3 in hemoglobin). Methemoglobin cannot bind with oxygen. Cyanosis and eventually death may occur if left untreated.
- O2 Saturation: Oxygen saturation is used to assess the oxygenation of hemoglobin and the adequacy of tissue oxygenation in the evaluation of pulmonary function. It is also used in the diagnosis and treatment of cyanosis.
- Oxyhemoglobin (O2Hb): The measurement of oxyhemoglobin is used to assess pulmonary function. Oxyhemoglobin is the fraction of total hemoglobin combined with oxygen. It is also used in the diagnosis and treatment of cyanosis.
- Total Hemoglobin: Oxygen is carried from the lungs throughout the body by hemoglobin present in red blood cells. Measurement of hemoglobin provides the clinician with information regarding the evaluation of chronic and acute anemias and also with information pertaining to the potential oxygen transport capability of the hemoglobin.
Performing Laboratory
CRMC Laboratory
CCMC Laboratory
