Sickle Cell Screen with Reflex to Hemoglobinopathy Evaluation

Test Code

37679Q

Quest Code

37679

CPT Codes
85660

Includes

If Sickle Cell Screen is positive, then Hemoglobinopathy Evaluation will be performed at an additional charge (CPT code(s): 83020, 85014, 85018, 85041).
Hemoglobinopathy Evaluation includes: Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW

Preferred Specimen

4 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

1 mL

Other Acceptable Specimens

Whole blood collected in an EDTA (tan-top), (pink-top) or (royal blue-top) tube

Instructions

Maintain specimen at room temperature. Do not centrifuge. Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results.

Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it
is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered. If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Clotted

Methodology
Solubility

Reference Range

See Laboratory Report

Clinical Significance

Screening test to determine presence of sickling hemoglobins (e.g. hemoglobin-S Hemoglobin C-Harlem).

Performing Laboratory

Quest Diagnostics - West Region

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.