Catecholamines, Fractionated, Plasma [314X]

Test Code
314X

CPT Codes
82384

Includes
Dopamine, Epinephrine, Norepinephrine and Total Catecholamines (calculated)

Preferred Specimen
4 mL plasma collected in a sodium heparin (green-top) tube

Minimum Volume
2.5 mL

Other Acceptable Specimens
Plasma collected in a lithium heparin (green-top), or sodium heparin, lead-free (tan-top) tube

Instructions
Plasma should be separated in a refrigerated centrifuge within 30 minutes of collection and then frozen immediately at -20°C in plastic vials. Each specimen will be invoiced separately.

Transport Container
Plastic screw-cap vial

Transport Temperature
Frozen

Specimen Stability
Room temperature: 6 hours
Refrigerated: 6 hours
Frozen: 30 days

Methodology
High Performance Liquid Chromatography (HPLC) with Electrochemical Detection

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Limitations
Recent surgery, traumatic injury, upright posture, cold, anxiety, pain, clonidine withdrawal, and concurrent acute or chronic illness may produce elevated results.

Reference Range
See Laboratory Report

Clinical Significance
The three catecholamines (norepinephrine, epinephrine, and dopamine) are the principal secretory products of neural tissue. Clinically, the measurement of circulating catecholamines is valuable in the diagnosis of catecholamine secreting tumors associated chiefly with hypertension (pheochromocytomas, neuroblastomas, and gangliomas) and with the evaluation of orthostatic hypotension.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.