Cryoglobulin Qualitative Analysis [383X]

Test Code

CPT Codes

Preferred Specimen
5 mL Serum red-top tube (no gel)

Minimum Volume
2.5 mL

After collection, allow specimen to clot at 37° C for 30-60 minutes. Place tube in a 37° C incubator or a waterbath. If not available, adjust tap water in a container to 37° C. Place collection tube into the container. Monitor temperature throughout clotting process. Centrifuge clotted tube in a pre-warmed centrifuge (run the centrifuge for 10 minutes prior to centrifuging the specimen). Pour serum into a plastic screw-capped vial and submit at room temperature.

Transport Container
Plastic screw-cap vial

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 3 days
Refrigerated: Unstable
Frozen: Unstable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Received frozen • Received refrigerated • Serum Separator Tube (SST®)

Visual Inspection

Setup Schedule
Set up: Monday-Sunday Evening; Report available: 4 days

Reference Range
None detected

Clinical Significance
Cryoglobulins are a group of proteins which precipitate from serum, plasma or urine upon exposure to cold.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.