Complement Component C4c

Test Code

CPT Codes

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 4 days
Frozen: 21 days


Setup Schedule
Set up: Sun-Fri; Report available: 1 day

Reference Range
  Male Female
<1 Year Not established Not established
1-14 Years 14-44 mg/dL 13-46 mg/dL
15-80 Years 15-53 mg/dL 15-57 mg/dL
≥81 Years Not established Not established

Clinical Significance
Decreased C4 level is associated with acute systemic lupus erythematosis, glomerulonephritis, immune complex disease, cryoglobulinemia, congenital C4 deficiency and generalized autoimmune disease.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.