Renin Activity, Plasma

Message
This test was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.


Test Code
10537


CPT Codes
84244

Preferred Specimen
3 mL plasma collected froman EDTA (lavender-top) tube


Minimum Volume
0.5 mL


Instructions
 Centrifuge and separate blood at room temperature. Avoid refrigerated temperatures. When submitting catheterization studies, it is recommended that the referring laboratory retain a portion of each sample.Patient should be ambulatory for 30 minutes prior to draw. Patient should be on a moderate sodium diet duringcollection. Avoid refrigeration to eliminate cryoactivation of prorenin to renin. 'Patient should refrain from taking medications, preferably 3 weeks prior to draw


Transport Container
Transport tube


Transport Temperature
Frozen


Specimen Stability
Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature; Received refrigerated


Methodology
Angiotensin I Generation ;Immunoassay

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
p.m. Daily


Report Available
2-4 days


Reference Range
0.25-5.82 ng/mL/h


Clinical Significance
See Renin Assays and Renin Direct in the Cardiovascular section of Test Application and Interpretation.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.