|
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
PROTIME AND INTERNATIONAL NORMALIZED RATIO
MessageProtime/INR: TUBE MUST BE FULL. DO NOT DRAW FROM A HEPARIN LOCK.
Test Code
PTINR
Preferred Specimen
LIGHT BLUE
Minimum Volume
Tube must be full.
Specimen Stability
24 hours
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, short draw tubes, clotted specimens. Ultracentrifuge grossly lipemic specimens.
Clinical Significance
PT is used to monitor oral anticoagulation therapy of Coumadin and Warfarin, which depresses the liver's production of factors II, VII, IX, and X by a process of copetitive inhibition with Vitamin K. Since PT measures Factors II, VII, and X, it can be used to monitor the drugs effect.