A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Drug Monitoring, Phosphatidylethanol (PEth), Blood
Test CodeDMPHB
Alias/See Also
12198
CPT Codes
80321 (HCPCS: G0480)
Includes
PEth 16:0/18:1 (POPEth) and PEth 16:0/18:2 (PLPEth)
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 30 days
Frozen: 30 days
Refrigerated: 30 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Non-whole blood samples • Non-EDTA (lavender-top) tube
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 3-5 days after receipt at the performing laboratory. Allow an additional two (2) days for transport to the performing laboratory.
Reference Range
PEth 16:0/18:1 (POPEth) | <20 ng/mL |
PEth 16:0/18:2 (PLPEth) | <20 ng/mL |
Clinical Significance
Alcohol abuse remains a significant public health challenge in the United States. As a long-term, specific and direct biomarker of alcohol consumption, Phosphatidylethanol (PEth) is a group of phospholipids formed in the presence of ethanol and incorporated into the phospholipid membrane of red blood cells. PEth detection is suggestive of ethanol ingestion over multiple days. PEth is detectable for 1-2 weeks. The predominant PEth homologues are PEth 16:0/18:1 (POPEth) and PEth 16:0/18:2 (PLPEth), which account for 37-46% and 26-28% of the total PEth homologues, respectively.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |
Additional Information
Annette Timmons
Last Updated: February 21, 2024