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CELIAC DISEASE PANEL, INFANT DIAGNOSTIC
MessageThis test should be ordered for patients less than two years old.
Test Code
CELIN
CPT Codes
82784, 86258, 86364 plus 86231 (if IgA is normal)
Includes
Includes: Total IgA, Tissue Transglutaminase IgA, Endomysial IgA antibody, Deamidated Gliadin IgA, and Pathologist interpretation. NOTE: If the Total IgA result is low, Tissue Transglutaminase IgG and deamidated Gliadin IgG will be performed in place of Tissue Transglutaminase IgA, Endomysial IgA antibody and Deamidated Gliadin IgA.
Preferred Specimen
1 Gold tube (gel separator)
Minimum Volume
1 mL
Other Acceptable Specimens
None
Instructions
Centrifuge for complete separation of serum and red cells. Separate and refrigerate or freeze within two (2) hours of collection time.
Transport Temperature
Refrigerate or freeze.
Specimen Stability
- 2-8°C up to 2 days; otherwise freeze at -20° or lower
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed or lipemic samples
Methodology
ELISA
Setup Schedule
T, Th
Report Available
Within 48 hours of day tested at the perfoming laboratory.
Reference Range
IgA levels are normal and both TTG IgA and EMA IgA levels are within normal limits.
Note: consider other causes for villous atrophy.
- In low risk patients (<5% disease probability), celiac disease is effectively excluded.
- In high risk patients (>5% disease probability), small bowel biopsy is recommended.
Note: consider other causes for villous atrophy.
Clinical Significance
This panel of serologic studies facilitates the diagnosis of celiac disease and follows the recommendations of the American Gastroenterological Association.
Performed By
Alverno Laboratories
Performing Laboratory
Alverno Central Lab
NIM1 (Immunology, Manual)
Last Updated: January 23, 2024