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CREATININE CLEARANCE

Message
  • Submit the Total Volume in mLs.
  • Submit Height in INCHES only (do not submit as feet and inches).
  • Submit Weight as a WHOLE NUMBER only (do not include "lbs" or any other text).


Test Code
NCRCL


CPT Codes
82575

Includes
Includes: Height, Weight, BSA (body surface area), Total volume, Serum creatinine, Urine creatinine, and Creatine clearance.


Preferred Specimen
2 containers:
  • 1 Gold tube (gel separator) AND
  • 24 Hour Urine Container without preservative (aliquot or transfer urine into a transfer tube and note the total volume)


Minimum Volume
  • 10 mL urine aliquot and
  • 0.5 mL serum


Other Acceptable Specimens
or 2 containers:
  • 1 Green tube (Lithium Heparin) and
  • 24 Hour Urine Container without preservative (aliquot or transferurine into a transfer tube and note the total volume)


Instructions
  • Mix the specimen well and measure the 24-Hour volume
  • Note the total volume in mLs.
  • Pour off 20 mL of urine into a separate plastic screw-cap container.
  • Note the patient height in inches.
  • Note the patient weight as a whole number.
  • Centrifuge blood tube(s) for complete separation of plasma/serum and red cells.
  • If whole blood was collected, aliquot plasma.
  • Refrigerate both urine and serum/plasma specimens until tested.


Transport Container
Urine:  Plastic screw-cap container
Serum or Plasma:  Standard transport tube


Transport Temperature
Refrigerate


Specimen Stability
2-8°C up to 4 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Incomplete collection


Methodology
Enzymatic Rate

Setup Schedule
M, T, W, Th, F, Sa, Sun


Report Available
Within 24 hours of receipt at the performing laboratory.


Reference Range
Creatinine Urine 24hr 0.7-1.6 G/24 hr
Creatinine 0.6-1.2 mg/dL
Creatinine Clearance 71-151 mL/min
eGFR Non-African American >60
eGFR African American >60


Clinical Significance
Used in the diagnosis and treatment of renal diseases, in monitoring renal dialysis, and as a calculation basis for measuring other urine analytes.


Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab  
NCHB1 (Chemistry, Beckman AU)


Last Updated: September 30, 2024


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.