Resources

SICKLE CELL SCREEN

Test Code
SICKL


CPT Codes
85660

Preferred Specimen
1 Lavender tube (EDTA)


Minimum Volume
0.1 mL EDTA whole blood


Instructions
Do not centrifuge; Refrigerate until testing.


Transport Temperature
Refrigerate


Specimen Stability
2-8°C up to 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Lipemia


Methodology
Solubility

Setup Schedule
M, T, W, Th, F


Report Available
Within 24 hours of receipt at the performing laboratory.


Reference Range
Negative
Recommend hemoglobin electrophoresis for Positive results 


Clinical Significance
Sickle cell anemia is an inherited disorder that leads to the production of an abnormal hemoglobin called hemoglobin S (Hb S or Hgb S).  Abnormal hemoglobin alters the shape of red cells which limits the ability of hemoglobin to transport oxygen to the tissues of the body.  In addition, the red blood cell life span decreases from 120 days to about 10-20 days. 

This test is used to aid in the diagnosis of Sickle Cell Disease or Sickle Cell Trait.


Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab  
NCH15 (Chemistry, Manual)


Last Updated: July 17, 2024


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.