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NEXT GENERATION SEQUENCING, MYELOID NEOPLASIA PANEL

Message

Physician must be contacted for approval before Add-On testing can be submitted





Must send sample with Hematopathology Patient Information Sheet.  Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.




Test Code
NGSMY


CPT Codes
81455

Includes
69 gene multiplexed DNA and RNA next generation sequencing panel. Assay detects single nucleotide variations, deletions / insertions, and gene fusions.


Minimum Volume
  • Whole blood - 1 mL
  • Bone Marrow aspirate - 0.5 mL


Other Acceptable Specimens
None


Instructions
Must include Hematopathology Patient Information Sheet with order.  Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.


Transport Temperature
Room temperature


Specimen Stability
  • 15-30°C up to 72 hours
  • 2-8°C up to 5 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
The following conditions will result in a rejeted specimen:
  • FFPE block
  • Frozen specimen
  • Clotted specimen


Methodology
Next Generation Sequencing

Setup Schedule
At minimum, this test will be batched once every two weeks


Report Available
Report available within 14 days of receipt at the performing laboratory.


Reference Range
No alterations identified within tested genes


Clinical Significance
Testing is indicated in patients with known myeloid malignancy (AML, MDS, MPN, MDS/MPN) or peripheral blood cytopenia for greater than 4 months where reactive causes have been reasonably excluded indicated for patients seeking further treatment for tumor.


Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab  
NMBNG (Molecular Biology, Next Gen Sequencing)

Additional Information
Hematopathology Patient Information Sheet

Last Updated: April 17, 2024


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.