A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Coxsackie A Antibodies, Serum
Test CodeCOXA1
Alias/See Also
37477
CPT Codes
86658 (x6)
Includes
Coxsackie Antibodies A2, A4, A7, A9, A10, A16
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Complement Fixation (CF)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days after receipt at the performing laboratory. Add three (3) days for transport.
Limitations
Culture does not usually support growth of coxsackie A viruses.
Reference Range
Coxsackie A2 Ab | <1:8 titer |
Coxsackie A4 Ab | <1:8 titer |
Coxsackie A7 Ab | <1:8 titer |
Coxsackie A9 Ab | <1:8 titer |
Coxsackie A10 Ab | <1:8 titer |
Coxsackie A16 Ab | <1:8 titer |
Interpretive Criteria
<1:8 | Antibody Not Detected |
≥1:8 | Antibody Detected |
Clinical Significance
Panel currently includes testing against A-2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1:8. Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |
Last Updated: May 4, 2023