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Epstein-Barr Virus DNA, Quantitative, Real-Time PCR

Test Code
EBVPC


Alias/See Also
10186


CPT Codes
87799

Preferred Specimen
1 mL whole blood collected in an EDTA (lavender-top) tube or
Plasma collected in an EDTA (lavender-top) tube or
Serum or
CSF collected in a sterile plastic leak-proof container


Minimum Volume
0.5 mL


Other Acceptable Specimens
Bronchoalveolar lavage collected in a sterile, plastic, leak-proof container


Instructions
CSF: Collect in a sterile, plastic container and store refrigerated or frozen.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable

All other specimens
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Heparin anticoagulant


Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Monday-Sunday Morning Report available: Next Day after receipt at the performing laboratory. Add two (2) days for transport.


Reference Range
EBV DNA, QN PCRNot Detected (copies/mL)
EBV DNA, QN PCRNot Detected (Log copies/mL)


Clinical Significance
Monitoring EBV DNA levels by quantitative PCR in patients at risk of EBV-associated lymphoproliferative disorders may allow timely recognition of virus reactivation and permit installment of antiviral treatment. Reportable Range is 200-2,000,000 copies/mL (2.30-6.30 Log Copies/mL).


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153


Last Updated: June 22, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.