Chromosome Analysis, Hematologic Malignancy

CHABM

14600

10 mL whole blood or 3 mL bone marrow collected in a sodium heparin (green-top) tube
Infants: 2-3 mL whole blood collected in a pediatric (3 mL) vacutainer

1 mL

Bone marrow or whole blood collected in: sodium heparin (royal blue-top), or sodium heparin lead-free (tan-top) tubes

Clinical history and reason for referral are required with test order. Previous bone marrow transplant or therapy information, if applicable, should be provided with test order.

Bone marrow: 3 mL or whole blood 10 mL, must contain 10% less mature myelocytes, pros, or blasts green vacutainer only. Infants 2-3 mL (in pediatric 3 mL vacutainer), must contain 10% myelocytes, pros or blasts. Ship at room temperature. Bone marrow transport medium is available upon request.

Note: See the "cytogenetics" section of the specimen collection guide for additional information. Other vacutainer tubes containing sodium heparin are acceptable.

This test may be replaced by one of the following if the completed test cannot be performed from the submitted specimen: a Tissue Culture for Hematologic Disorder code; or with a Cytogenetics Communication, if a communication is required.

Room temperature

Room temperature: See Collection Instructions
Refrigerated: See Collection Instructions
Frozen: See Collection Instructions

Received frozen

Set up: Mon-Sat; Report available: 8 days after receipt at the performing laboratory. Add two (2) days for transport.

See Laboratory Report

Cytogenetics of hematologic disorders attempts to define and interpret chromosomal aberrations that occur in neoplastic cells associated with leukemia, lymphoma and other hematologic malignancies. Chromosome abnormalities in cancer cells of patients with malignant hematologic disorders including acute and chronic myeloid and lymphoid leukemias, myelodysplastic and myeloproliferative disorders, lymphomas and unexplained anemias may correlate with the diagnosis, prognosis, treatment and etiology of disease.