Extended Myositis Specific Antibody (MSA) Panel

Test Code

EMSAP

Alias/See Also

10257

CPT Codes
84182 (x6), 86235 (x5), 83520, 83516

Includes

Myositis Specific 11 Antibodies Panel (Jo-1, PL-7, PL-12, EJ, OJ, SRP, MI-2 alpha and beta, MDA5, TIF1, NXP-2)
3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Antibody (IgG)
Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG)

Preferred Specimen

1.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.9 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Moderate to gross hemolysis • Received room temperature • Serum separator tube (SST)

Methodology
Chemiluminescence (CL) • Enzyme Linked Immunosorbent Immunoassay (ELISA) • Line Blot

Setup Schedule

Tuesday, Thursday, Saturday Morning Report available: 3 Days after receipt at the performing laboratory. Add three (3) days for transport.

Reference Range

See individual tests

Clinical Significance

The Extended Myositis Specific Antibody (MSA) panel is designed as an aid for the diagnosis of myopathies associated with autoantibody production. These include inflammatory myopathies (polymyositis, anti-synthetase syndrome, dermatomyositis), necrotizing myopathies, including statin associated myopathy, and inclusion body myositis.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

Last Updated: June 22, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.