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Histoplasma Antibody Panel, CF and ID, Serum
Test CodeHPACI
Alias/See Also
37094
CPT Codes
86698 (x3)
Includes
Histoplasma Antibody, Immunodiffusion, Serum
Histoplasma Antibody, Complement Fixation, Serum
Histoplasma Antibody, Complement Fixation, Serum
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Plastic vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly icteric • Grossly lipemic
Methodology
Complement Fixation (CF) • Immunodiffusion (ID)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days after receipt at the performing laboratory. Add two (2) days for transport.
Reference Range
See Laboratory Report
Clinical Significance
Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis, and complement fixation testing detects antibodies in approximately 90% of patients.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: August 4, 2023