A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Copper
Test CodeCOPPR
Alias/See Also
363
CPT Codes
82525
Preferred Specimen
2 mL plasma collected in an EDTA (royal blue-top) tube or sodium heparin (royal blue-top) tube
Minimum Volume
0.7 mL
Other Acceptable Specimens
Serum collected in: No additive (royal blue-top) tube
Instructions
Separate serum or plasma from cells within 2 hours. Transfer separated serum or plasma to a plastic, acid-washed or metal-free vial.
Transport Container
Acid-washed or metal-free vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 10 days
Frozen: 30 days
Refrigerated: 10 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Serum or plasma not separated from cells • Samples submitted in non-trace metal or non-acid washed containers
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: Same day after receipt at the performing laboratory. Add two (2) days for transport.
Reference Range
≤5 Months | 38-104 mcg/dL | |
6-11 Months | 24-152 mcg/dL | |
12 Months-23 Months | 76-193 mcg/dL | |
1-3 Years | 87-187 mcg/dL | |
4-5 Years | 56-191 mcg/dL | |
6-9 Years | 117-181 mcg/dL | |
10-13 Years | 87-182 mcg/dL | |
14-17 Years | 75-187 mcg/dL | |
≥18 Years | 70-175 mcg/dL |
Clinical Significance
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions and during the third trimester of pregnancy. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: June 22, 2023