Cardio IQ® APOE Genotype

Test Code

APOAR

Alias/See Also

90649
Apolipoprotein E Genotyping

CPT Codes
81401

Preferred Specimen

4 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

2 mL

Instructions

Multiple (up to 8) cardiovascular-related genetic tests can be performed on a single specimen. A second EDTA (lavender-top) tube is required if non-genetic tests are simultaneously ordered that require an EDTA (lavender-top) tube. For whole blood samples, follow normal phlebotomy procedures.

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: 30 days

Methodology
Real-Time Polymerase Chain Reaction (PCR)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon, Wed-Sat; Report available: 3-5 days

Report Available

Franciscan Alliance EPIC users: scanned report will be in the results section
Non-Franciscan Alliance EPIC users: refer to normal method for separate report delivery

Reference Range

See Laboratory Report

Clinical Significance

This test determines the subtypes of APOE which will aid in the risk assessment of Coronary Heart Disease (CHD) and Hyperlipoproteinemia.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: December 29, 2025

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.