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Blood Ketone
Test CodeBKETN
Alias/See Also
Beta Hydroxybutyrate, Ketone, Acetone
Preferred Specimen
1.0 mL Serum (0.5 mL minimum)
Other Acceptable Specimens
Lithium heparin plasma
Transport Container
Red top or SST tube; PST (light green top) also acceptable
Specimen Stability
Room temperature: 8 hours, Refrigerated: 24 hours, Frozen: Not recommended
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens are unacceptable.
Reference Range
0.02 - 0.27 mmol/L
Clinical Significance
Useful for diagnosis and monitoring of therapy for diabetic ketoacidosis and for any patient presenting to the emergency room with documented hypoglycemia, acidosis, alcohol ingestion or unexplained increase in the anion gap.
In pediatric patients, the presence or absence of ketonemia/uria is an essential component in the differential diagnosis of inborn errors of metabolism.
In pediatric patients, the presence or absence of ketonemia/uria is an essential component in the differential diagnosis of inborn errors of metabolism.