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Urine Phencyclidine Screen (PCP)
Test CodeUPCPT
Alias/See Also
Angel Dust, PCP
Preferred Specimen
15 mL urine (2 mL minimum)
Instructions
Freshly voided urine specimens should be used for testing. No additives or preservatives are needed. Adulteration of the urine specimen may cause erroneous results. If adulteration is suspected, obtain a fresh specimen. Deliver specimen to laboratory immediately.
Transport Container
Urine collection cup
Specimen Stability
Room temperature: 4 hours, Refrigerated: 24 hours, Freeze if storage for longer than 24 hours is required.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Do NOT use boric acid as a preservative.
Limitations
• A positive result indicates the likely presence of phencyclidine but does not indicate or measure intoxication.
• The presence of phencyclidine in urine is only an indication of recent exposure to or use of phencyclidine.
• The psychological and physiological effects of phencyclidine do not necessarily correlate with urinary concentration.
• A positive PCP result indicates the likely presence of drug and its metabolites. The PCP method cannot fully quantitate the concentration of individual components.
• Interpretation of results must take into account that urine concentrations vary extensively with fluid intake, and other biological variables.
• There is a possibility that other substances and/or factors not listed above may interfere with the test and cause false results, e. g., technical or procedural error.
• The presence of phencyclidine in urine is only an indication of recent exposure to or use of phencyclidine.
• The psychological and physiological effects of phencyclidine do not necessarily correlate with urinary concentration.
• A positive PCP result indicates the likely presence of drug and its metabolites. The PCP method cannot fully quantitate the concentration of individual components.
• Interpretation of results must take into account that urine concentrations vary extensively with fluid intake, and other biological variables.
• There is a possibility that other substances and/or factors not listed above may interfere with the test and cause false results, e. g., technical or procedural error.
Reference Range
None detected
Clinical Significance
Phencyclidine, also known as PCP and "angel dust," is a synthetic drug that was originally developed for its anesthetic properties but is now a drug of abuse used solely for its potent hallucinogenic effects. Measurements obtained are used in the diagnosis and treatment of phencyclidine use or overdose. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Other chemical confirmation methods are available. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.
