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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Urine Opiates Screen
Test CodeUOPIT
Alias/See Also
Morphine, OPI, Opiate screen urine
Preferred Specimen
15 mL urine (2 mL minimum)
Instructions
Freshly voided urine specimens should be used for testing. No additives or preservatives are needed. Adulteration of the urine specimen may cause erroneous results. If adulteration is suspected, obtain a fresh specimen. Deliver specimen to laboratory immediately.
Transport Container
Urine collection cup
Specimen Stability
Room temperature: 4 hours, Refrigerated: 24 hours, Freeze if storage for longer than 24 hours is required.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Do NOT use boric acid as a preservative.
Limitations
• A positive result indicates the likely presence of opiates but does not indicate or measure intoxication.
• The presence of opiates in urine is only an indication of recent exposure to or use of opiates.
• The psychological and physiological effects of opiates do not necessarily correlate with urinary concentration.
• A positive OPI result indicates the likely presence of drug and its metabolites. The OPI method cannot fully quantitate the concentration of individual components.
• Interpretation of results must take into account that urine concentrations vary extensively with fluid intake, and other biological variables.
• There is a possibility that other substances and/or factors not listed above may interfere with the test and cause false results, e.g., technical or procedural errors.
• The presence of opiates in urine is only an indication of recent exposure to or use of opiates.
• The psychological and physiological effects of opiates do not necessarily correlate with urinary concentration.
• A positive OPI result indicates the likely presence of drug and its metabolites. The OPI method cannot fully quantitate the concentration of individual components.
• Interpretation of results must take into account that urine concentrations vary extensively with fluid intake, and other biological variables.
• There is a possibility that other substances and/or factors not listed above may interfere with the test and cause false results, e.g., technical or procedural errors.
Reference Range
None detected
Clinical Significance
Opiates are a class of compounds that includes morphine, codeine, and heroin. Morphine and codeine are naturally occurring alkaloids that are found in opium, a substance exuded from the unripe seed pod of the opium poppy Papaver somniferum. Heroin is a semisynthetic derivative of morphine. Measurements of opiate levels in urine are used in the diagnosis and treatment of opiates use or overdose.
