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Tobramycin Peak

Test Code
TOBRP


Alias/See Also
Nebcin, TOBRA


Preferred Specimen
1.0 mL plasma (0.5 mL minimum)


Instructions
Collect specimen thirty (30) minutes after completion of infusion or ninety (90) minutes after injection.


Transport Container
PST (light green top). Red top and SST also acceptable


Specimen Stability
Room temperature: 8 hours, Refrigerated: 3 days, Frozen: 1 month


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens are unacceptable.


Limitations
Aminoglycosides structurally similar to tobramycin (e.g. kanamycin) may significantly cross-react with this method. Therefore, the TOBR method cannot reliably be used for patients receiving these antibiotics separately or in combination with tobramycin.


Reference Range
4.0 - 8.0 ug/mL


Clinical Significance
Tobramycin is an aminoglycoside antibiotic. TOBR test results may be used in the diagnosis and treatment of tobramycin overdose and in monitoring levels of tobramycin to ensure appropriate therapy and minimize ototoxicity and/or nephrotoxicity.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.