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Phosphorus
Test CodePHOS
Alias/See Also
PO4, Inorganic Phosphorus, PHOS
Preferred Specimen
1.0 mL plasma (0.5 mL minimum)
Transport Container
PST (light green top). Red top and SST also acceptable
Specimen Stability
Room temperature: 8 hours, Refrigerated: 2 days, Frozen: 1 month
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens are unacceptable.
Reference Range
Age | Female | Male |
Adult (>18 years): | 2.5 - 4.9 mg/dL | 2.5 - 4.9 mg/dL |
Pediatric: | ||
0– 30 days | 3.1-7.7 | 2.8-7.0 |
1 – 2 months | 3.1-7.2 | 3.1-6.6 |
3 – 12 months | 3.1-6.8 | 3.1-6.6 |
13 – 23 months | 3.1-6.3 | 3.1-6.2 |
2 – 12 years | 3.1-5.9 | 3.1-5.9 |
13 – 15 years | 3.1-5.5 | 3.1-5.3 |
16 –18 years | 3.1-4.8 | 3.1-5.1 |
Clinical Significance
Serum phosphorus levels alone are of limited diagnostic value and should be correlated with serum calcium levels. Increased phosphorus with decreased calcium suggests either hypoparathyroidism or renal disease. Decreased phosphorus and increased calcium suggests hyperparathyroidism or sarcoidosis. When both calcium and phosphorus are decreased diagnostic considerations include malabsorption, vitamin D deficiency and renal tubular acidosis. Increased phosphorus and normal or increased calcium suggests milk-alkali syndrome or hypervitaminosis D.