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Cholesterol, HDL
Test CodeHDL
Alias/See Also
High Density Lipoprotein, HDL Cholesterol, HDL
Preferred Specimen
1.0 mL plasma (0.5 mL minimum)
Instructions
Blood should be collected after a 12-hour period of fasting by normal procedure.
Transport Container
PST (light green top). Red top and SST also acceptable
Specimen Stability
WOMC & FWMC
Room temperature: 8 hours, Refrigerated: 1 week, Frozen: 3 months
SGMC
Room Temperature: 8 hours, Refrigerated: 8 days, Frozen: 30 days
Room temperature: 8 hours, Refrigerated: 1 week, Frozen: 3 months
SGMC
Room Temperature: 8 hours, Refrigerated: 8 days, Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens are unacceptable.
Reference Range
| Age | Female | Male |
| Adult (>19 years): | >39 mg/dL | >39 mg/dL |
| Pediatric: | ||
| 5 – 14 years | 37-75 | 38-76 |
| 15 – 19 years | 36-76 | 31-65 |
Clinical Significance
HDL Cholesterol is a useful test to assess the risk for cardiovascular disease. It is increased following regular exercise, moderate alcohol consumption and with oral estrogen therapy. Decreased levels are associated with obesity, stress, cigarette smoking and diabetes mellitus. For every 1 mg/dL decrease in HDL, the risk for cardiovascular disease increases by 2-3%.
