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Bilirubin, Total
Test CodeTBILI
Alias/See Also
Bili, Total Bili, Total bilirubin
Preferred Specimen
1.0 mL plasma (0.5 mL minimum)
Instructions
Protect from light
Transport Container
PST (light mint green top). Red top and SST also acceptable
Specimen Stability
Room temperature: 8 hours, Refrigerated: 5 days, Frozen: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens are unacceptable.
Reference Range
| Age | Male/Female |
| Adult (> 17 years): | < 1.0 mg/dL |
| Pediatric: | |
| 0 – 24 hours | < 5.1 |
| 1 – 2 days | < 7.2 |
| 3 days – 30 days | < 10.3 |
| 1 month – 17 years | < 0.8 |
Clinical Significance
Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder block. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders. The increase in total bilirubin associated with obstructive jaundice is primarily due to the direct (conjugated) fraction. Both direct and indirect bilirubins are increased in the serum with hepatitis.
