Bilirubin, Neonatal

Test Code

NBIL

Alias/See Also

Neo Bili, Neonatal Bili Profile, Bilirubin Neonate (total and direct), Neonatal Bilirubin (total and direct), Bilirubin Neonate

Includes

Total Neo Bilirubin, Unconjugated Bilirubin, Direct Neo Bilirubin

Preferred Specimen

serum

Instructions

Protect from light

Transport Container

Micro Amber tube

Specimen Stability

Room temperature: 8 hours, Refrigerated: 7 days, Frozen: 6 months

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly hemolyzed specimens are unacceptable.

Reference Range

Bilirubin, total	Age	Male/Female
	0 – 24 hours	< 5.1
	1 – 2 days	< 7.2
	3 days – 30 days	< 10.3
	1 month – 17 years	< 0.8
Bilirubin, direct	all	0.0 – 0.3 mg/dL
Bilirubin, indirect	all	0.6 – 10.5 mg/dL

Clinical Significance

In the newborn patient with hemolytic jaundice and neonatal jaundice, the increase in the total bilirubin is primarily due to the indirect (unconjugated) bilirubin fraction. Rh, ABO, or other blood group incompatibilities may cause this jaundice, by hepatic immaturity, or by hereditary defects in bilirubin conjugation.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.