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Bilirubin, Direct
MessagePerformed in Chemistry
Test Code
BILID
CPT Codes
82248
Preferred Specimen
Green Top LiHep, Plasma
Gold/Amber Tube
WyMCC - SST
Note: Patients Less than 30 days old
Preferred Tube Type: Green/Gold/Amber Microtainer 1 mL
Patient Greater than 30 days old
Preferred Tube Type: Green or Gold 4mL
Gold/Amber Tube
WyMCC - SST
Note: Patients Less than 30 days old
Preferred Tube Type: Green/Gold/Amber Microtainer 1 mL
Patient Greater than 30 days old
Preferred Tube Type: Green or Gold 4mL
Other Acceptable Specimens
Gold/SST, Red Top
Instructions
No Hemolysis
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Clinical Significance
Bilirubin is formed in the reticuloendothelial system during the degradation of
aged erythrocytes. The heme portion from hemoglobin and from other hemecontaining proteins is removed, metabolized to bilirubin, and transported as a
complex with serum albumin to the liver. In the liver, bilirubin is conjugated with
glucuronic acid for solubilization and subsequent transport through the bile duct
and elimination via the digestive tract. Diseases or conditions which, through
hemolytic processes, produce bilirubin faster than the liver can metabolize it,
cause the levels of unconjugated (indirect) bilirubin to increase in the circulation.
Liver immaturity and several other diseases in which the bilirubin conjugation
mechanism is impaired cause similar elevations of circulating unconjugated
bilirubin. Bile duct obstruction or damage to hepatocellular structure causes
increases in the levels of both conjugated (direct) and unconjugated (indirect)
bilirubin in the circulation.
aged erythrocytes. The heme portion from hemoglobin and from other hemecontaining proteins is removed, metabolized to bilirubin, and transported as a
complex with serum albumin to the liver. In the liver, bilirubin is conjugated with
glucuronic acid for solubilization and subsequent transport through the bile duct
and elimination via the digestive tract. Diseases or conditions which, through
hemolytic processes, produce bilirubin faster than the liver can metabolize it,
cause the levels of unconjugated (indirect) bilirubin to increase in the circulation.
Liver immaturity and several other diseases in which the bilirubin conjugation
mechanism is impaired cause similar elevations of circulating unconjugated
bilirubin. Bile duct obstruction or damage to hepatocellular structure causes
increases in the levels of both conjugated (direct) and unconjugated (indirect)
bilirubin in the circulation.
Performing Laboratory
On-site
