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Heparin Assay - LMWH Anti-Xa
MessagePerformed in the Coagulation Dept.
Performed at BUMCT for BUMCS
Perfromed at WyMCC, BTMC, BBMC and BDMC
Performed at BUMCP, for remaining AZ locations
All remaining AZ Locations: If Ordered ES or ST then send via ST Courier to BUMCP
Performed at BUMCT for BUMCS
Perfromed at WyMCC, BTMC, BBMC and BDMC
Performed at BUMCP, for remaining AZ locations
All remaining AZ Locations: If Ordered ES or ST then send via ST Courier to BUMCP
Test Code
LMWH
Alias/See Also
Heparin Concentration LMW
Heparin Assay Anti Xa LMW
Low Molecular Weight Heparin Assay
Heparin Assay Anti Xa LMW
Low Molecular Weight Heparin Assay
Preferred Specimen
3.2% sodium citrate - blue top tube
Instructions
Note: All sites sending to BUMCP and BDMC must separate plasma and freeze before sending out.
The light blue capped tubes, containing 3.2% buffered sodium citrate, used for coagulation testing must be allowed to fill completely (after filling a small air space will normally be present). We cannot accept a short filled tube. Centrifuge within 1 hour of collection. Complete testing within 4 hours of collection or transfer specimen to polypropylene plastic tube using a plastic transfer pipette. Freeze plasma < -20°C
The light blue capped tubes, containing 3.2% buffered sodium citrate, used for coagulation testing must be allowed to fill completely (after filling a small air space will normally be present). We cannot accept a short filled tube. Centrifuge within 1 hour of collection. Complete testing within 4 hours of collection or transfer specimen to polypropylene plastic tube using a plastic transfer pipette. Freeze plasma < -20°C
Transport Temperature
Frozen
Specimen Stability
| · 4 hours at 2-8°C or 20°C, |
| · 2 weeks at -20°C |
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
| · clotted specimens |
| · underfilled or overfilled tube |
| · collection in 3.8% Citrate |
| · specimens collected in expired tubes |
| · serum samples |
| · specimen past stability |
| · thawed frozen samples |
| · Hemolyzed, icteric, or lipemic sample |
Setup Schedule
Reference Range
| Reference Range: LMW Heparin <0.04 IU/mL (WYMCC <0.11 IU/mL) |
| Therapeutic Range: LMW Heparin 0.6 – 1.0 IU/mL |
Clinical Significance
Unfractionated Heparin (UFH) and Low molecular weight heparins (LMWH) are used for the prevention and treatment of thromboembolic diseases. The quantitative determination of plasma UFH and LMWH levels are useful for monitoring treatment efficacy.
