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Cryptococcus Antigen CSF, Reflex titer if ind
MessageTesting for BUMCT and BUMCS is performed at BUMCT.
Testing for Wyoming Medical Center is performed on site.
Testing for Wyoming Medical Center is performed on site.
Test Code
CryptAg SF
Preferred Specimen
CSF – aseptically collected in a sterile
screw-cap container.
screw-cap container.
Minimum Volume
Minimum: 1.0mL for CSF.
Specimen Stability
Stability and Storage
Storage Temperatures:
• Ambient: Not acceptable.
• Refrigerated: 2-8°C up to 72 hours
• Frozen: ≤20°C, up to 4 weeks (never
repeatedly thawed and refrozen.)
Storage Temperatures:
• Ambient: Not acceptable.
• Refrigerated: 2-8°C up to 72 hours
• Frozen: ≤20°C, up to 4 weeks (never
repeatedly thawed and refrozen.)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Bloody or cloudy CSF
Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.
Additional Information
Cryptococcus Antigen, CSF