PBG Deaminase, Whole Blood

Message

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

PBGD

Alias/See Also

Acute Intermittent Porphyria (AIP).
MAYO code PBGD

CPT Codes
82657

Preferred Specimen

4 mL Whole Blood collected in a Sodium Heparin (Green Top) tube

Patient Preparation
Abstinence from alcohol for at least 24 hours prior to specimen collection is essential as ethanol induces porphobilinogen deaminase (PBGD) activity, which may lead to a false-normal result.

Minimum Volume

3 mL

Other Acceptable Specimens

Lavender top K3EDTA tube
or
green top (Lithium Heparin) tube

Transport Container

Sodium Heparin Green Top tube

Transport Temperature

Refrigerated

Specimen Stability

Room Temperature: 7 Days
Refrigerated: 8 Days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis

Methodology
Enzymatic End point/Spectrofluorometric

Setup Schedule

Tuesday, Thursday

Report Available

2 - 4 days

Clinical Significance

Confirmation of a diagnosis of acute intermittent porphyria (AIP)

Performing Laboratory
MAYO CLINIC LABORATORIES
200 FIRST ST
ROCHESTER, MN 55905

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.