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MET (7Q31), FISH, Tissue
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
M7Q31
Alias/See Also
Mayo Code METF
CPT Codes
88271x2, 88291 – DNA probe, each (first probe set), Interpretation and report 88271x2 – DNA probe, each; each additional probe set (if appropriate) 88271x1 – DNA probe, each; coverage for sets containing 3 probes (if appropriate) 88271x2 – DNA probe, each; coverage for sets containing 4 probes (if appropriate) 88271x3 – DNA probe, each; coverage for sets containing 5 probes (if appropriate) 88274 w/modifier 52 – Interphase in situ hybridization, <25 cells, each probe set (if appropriate) 88274 – Interphase in situ hybridization, 25 to 99 cells, each probe set (if appropriate) 88275 – Interphase in situ hybridization, 100 to 300 cells, each probe set (if appropriate)
Preferred Specimen
Submit only 1 of the following specimens:
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Minimum Volume
Two consecutive, unstained, 5-micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Other Acceptable Specimens
Acceptable: Slides Collection
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Instructions
1. A pathology report is required in order for testing to be performed. Acceptable pathology reports include working drafts, preliminary pathology or surgical pathology reports.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
Transport Temperature
Ambient
Methodology
Fluorescence In Situ Hybridization (FISH)
Setup Schedule
Monday - Friday
Report Available
7 - 10 days
Clinical Significance
Providing prognostic information and guiding treatment primarily for patients with lung, gastric, and renal tumors as well as other tumor types
Performing Laboratory
MAYO CLINIC LABORATORIES
200 FIRST ST
ROCHESTER, MN 55905
